Gene-based vaccine approaches


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Gene-based vaccine approaches Wednesday, February 3, 2021 • OA12 • 3:00 PM > 4:00 PM • Gene-based vaccine approaches • Live channel 1 3:00 PM • OA12.01 • Fine-tuning of <i>in vitro</i> transcribed mRNA for optimising a vaccine platform against HIV-1 See abstract 3:08 PM • OA12.02 • Comparison of co-immunization of DNA and protein in the same anatomical sites and in contralateral sites to identify mechanisms of protective immune response See abstract 3:16 PM • OA12.03 • Tetravalent immunogen assembled fromÂ conserved regions of HIV-1 and delivered asÂ mRNA demonstrates potent preclinical T cellÂ immunogenicity and breadth See abstract 3:24 PM • OA12.04LB • A VSV-based HIV-1 vaccine provides protection in macaques against low dose cross-clade SHIVenv_SF162_P3 challenge See abstract 3:32 PM • OA12.05 • Improved in vitro expression and in vivo immunogenicity of a candidate MVA-vectored HIV-1 vaccine compared to SAAVI MVA-C See abstract 3:40 PM • OA12.06 • Live Q&A See abstract